"And they gave him to drink wine mingled with myrrh: but he received it not." (KJV)
Let me tell you what this particular verse tells me.
First, by refusing it, He proved that He was in total control of the situation. He did not lose sight of the reason why He was there on the cross.
Second, He did not want to kill the pain. The purpose of the wine was to intoxicate the body so that it will lessen the pain and misery. The Lord wanted to feel every pain and burden of the cross. He tasted death with each drop of blood and without any distraction. He showed that he did not need any outward means to cheer him, nor he had any desire to alleviate his sorrows. He was not afraid to meet death in all its terrors. He was indeed the perfect sacrifice for our sins.
Finally, this act further proves that the Lord Jesus was not an ordinary human being like all of us who would normally drink the wine to get rid of the awful pain. He is the Son of God; God manifested in flesh.
The Lord Jesus was crucified for a purpose. Bringing us to Heaven was His main focus.
Nothing could ever distract Him. His eyes were occupied and set on His goal. He could only see the effect of his death, the brighter side of the resurrection. He endured in behalf of us what we could not do.
When I look at the cross, I could only see a PERFECT JOB!